Mainz is one of the centers of the German wine economy as a center for wine trade and the seat of the state's wine minister. Due to the importance and history of the wine industry for the federal state, Rhineland-Palatinate is the only state to have such a department.
Since 2008, the city is also member of the Great Wine Capitals Global Network (GWC), an association of well-known wineculture-cities of the world.
Many wine traders also work in the town. The sparkling wine producer Kupferberg produced in Mainz-Hechtsheim and even Henkell — now located on the other side of the river Rhine — had been founded once in Mainz. The famous Blue Nun, one of the first branded wines, had been marketed by the family Sichel.
Mainz had been a wine growing region since Roman times and the image of the wine town Mainz is fostered by the tourist center. The Haus des Deutschen Weines (English: House of German Wine), is located in beside the theater. The Mainzer Weinmarkt (wine market) is one of the great wine fairs in Germany.